The region-wide STOXX 600 fell 0.4%. For the year so far, it is down 12.8%.

After a brief jump this week, global markets are nervous about Beijing's move to further relax COVID curbs as surging infections in China dimmed hopes of a swift recovery in the world's second-largest economy.

China-exposed luxury firms such as LVMH and Richemont weighed on the European index in early trading.

Energy stocks fell 0.6%, while miners dipped 0.3%, tracking weakness in commodity prices.

Consumer staples such as Nestle and L'Oreal SA fell 1.2% and 0.5%, respectively.

Novartis AG slipped 0.5% after the Swiss drugmaker said it will pay $245 million to resolve civil litigation accusing the company of trying to delay the launch in the U.S of generic versions of the Exforge blood pressure treatment.

(Reporting by Bansari Mayur Kamdar in Bengaluru; editing by Uttaresh.V)