He made those remarks on NBC's "Late Night with Seth Meyers".
This came as Arab countries have voiced fears should the fighting continue into Ramadan it will further stoke regional tensions and while momentum on ceasefire negotiations gathered pace in Qatar.
On the show, Biden revealed there was an agreement in principle for a ceasefire between Israel and Hamas, which could be in place by this time next week.
He said such a pause would give time for remaining hostages Hamas captured on October 7 to be released.
The group took over 250 hostages when it stormed across southern Israel on October 7 and killed over 1,200 people.
Israel's subsequent ground assault led to nearly 30,000 people killed, according to Gaza health authorities.
In his Late Night appearance Monday, Biden said Israel risks losing support from the rest of the world.
He added that the Israeli government made a commitment to him to try to evacuate large portions of Rafah, which has millions of displaced Palestinians who fled other war-torn parts of Gaza before Israeli forces move in to target what he called the 'remainder' of Hamas.
The last deal to suspend fighting came in November where Hamas released more than 100 hostages and Israel freed about three times as many Palestinian prisoners.
In recent weeks, both Israel and Hamas have publicly maintained positions that are far apart for a potential truce while blaming the other for delays.
Israel continues to say it will not end the war until Hamas is destroyed.
While Hamas says it will not free hostages without an agreement to end the war.
As Biden gears up for a bid at re-election this November, he has seen support among young Americans and left-leaning progressive voters sink as a result of his staunch support for Israel and the sky-high death tolls in Gaza.
