Mark R.L. Krul
Founder at Aglaia Management BV
Profile
Dr. Krul has a background in molecular biology and immunology and over 12 years experience in anticancer drug development.
Before founding AGLAIA BioMedical Ventures he was Program Director of the NDDO Research Foundation.
He held several positions at NDDO Oncology BV, formerly the EORTC New Drug Development Office, with respect to oncology drug development strategies from 1997-2002 and was secretary of the Dutch Society of Gene Therapy.
From 1993 till 1997 Dr. Krul has been Research Manager of the European Cancer Center.
He has headed the Department of Molecular Virology at the National Institute of Public Health and Environmental Protection from 1989 till 1993.
In this period he organized a European concerted action “Immunology of human papillomaviruses and vaccine development”, also being the topic of his PhD thesis, which he defended at the University of Utrecht in 1996.
Mark R.L. Krul active positions
| Companies | Position | Start |
|---|---|---|
Aglaia Management BV
 Aglaia Management BV Investment ManagersFinance Aglaia Management BV is an independent venture capital investment firm headquartered in Bilthoven, the Netherlands. In 2003, Aglaia was co-founded by Mark Krul and Karl Rothweiler. | Founder | 15/04/2010 |
ORCA Therapeutics BV
 ORCA Therapeutics BV Pharmaceuticals: GenericHealth Technology ORCA Therapeutics BV designs and develops virotherapy drugs. The firm is a biopharmaceutical company focusing on the development of new anti-cancer treatments using Oncolytic Replication Competent Agents. It has a platform of technologies which are predominantly based on engineered oncolytic adenoviruses. The company was founded in 2005 and is headquartered in Nijmegen, the Netherlands. | Director/Board Member | 03/07/2009 |
SomantiX BV
 SomantiX BV Miscellaneous Commercial ServicesCommercial Services SomantiX BV develops imaging and therapy of cancer through targeting of tumor blood vessels. The firm offers Somantix’ screening platform which is in combination with the binder generation technologies that allows validation of new therapeutic targets and development of new cancer medicines. The company was founded in 2008 and is headquartered in Utrecht, Netherlands. | Chief Executive Officer | 09/06/2011 |
Inthera Bioscience AG
 Inthera Bioscience AG BiotechnologyHealth Technology Inthera Bioscience AG engages in the research in as well as development, production, and distribution of pharmaceutical, biological, and other products used in the fields of human and veterinary medicine. It also provides related consultancy services. The company was founded by Ulrich Kessler and Paramjit Singh Arora on September 20, 2013 and is headquartered in Zurich, Switzerland. | Director/Board Member | - |
Cristal Delivery BV
 Cristal Delivery BV Pharmaceuticals: MajorHealth Technology Cristal Delivery BV develops and manufactures nanomedicines for therapeutic drug optimization. It offers pipeline, oncology, and inflammation programs. The company was founded by Joost J. M. Holthuis and Cristianne Rijcken in April 2011 and is headquartered in Maastricht, the Netherlands. | Director/Board Member | - |
Macrophage Pharma Ltd.
 Macrophage Pharma Ltd. BiotechnologyHealth Technology Macrophage Pharma Ltd. engages in research and experimental development on biotechnology. The company is headquartered in Berkhamsted, the United Kingdom. | Director/Board Member | 01/01/2017 |
Former positions of Mark R.L. Krul
| Companies | Position | End |
|---|---|---|
NDDO Oncology BV
 NDDO Oncology BV Miscellaneous Commercial ServicesCommercial Services Part of Syneos Health, Inc., NDDO Oncology BV provides product development support to pharmaceutical and biotechnology companies. The company is based in Amsterdam, Netherlands. The Dutch company was founded by Herbert Michael Pinedo. NDDO Oncology was acquired by Syneos Health NC LLC, part of Syneos Health, Inc. from December 31, 2010 on December 01, 2005. | Corporate Officer/Principal | - |
| The European CanCer Organisation | Corporate Officer/Principal | - |
| Rijksinstituut Voor Volksgezondheid En Milieu | Corporate Officer/Principal | 02/01/1993 |
| ░░░░░░░ ░░ | ░░░░░░░░░░░░░░ ░░░░░░ | - |
| ░░░░░ ░░░░░░░░░░░░░░░ ░░ | ░░░░░░░░░░░░░░ ░░░░░░ | - |
Training of Mark R.L. Krul
| University of Utrecht | Doctorate Degree |
Experiences
Positions held
Connections
1st degree connections
1st degree companies
Male
Female
Members of the board
Executives
Linked companies
| Listed companies | 1 |
|---|---|
| MERUS N.V. | Health Technology |
| Private companies | 14 |
|---|---|
NDDO Oncology BV
NDDO Oncology BV Miscellaneous Commercial ServicesCommercial Services Part of Syneos Health, Inc., NDDO Oncology BV provides product development support to pharmaceutical and biotechnology companies. The company is based in Amsterdam, Netherlands. The Dutch company was founded by Herbert Michael Pinedo. NDDO Oncology was acquired by Syneos Health NC LLC, part of Syneos Health, Inc. from December 31, 2010 on December 01, 2005. | Commercial Services |
Aglaia Management BV
Aglaia Management BV Investment ManagersFinance Aglaia Management BV is an independent venture capital investment firm headquartered in Bilthoven, the Netherlands. In 2003, Aglaia was co-founded by Mark Krul and Karl Rothweiler. | Finance |
ISA Pharmaceuticals BV
 ISA Pharmaceuticals BV Pharmaceuticals: MajorHealth Technology ISA Pharmaceuticals BV operates as a clinical-stage immunotherapy company. The firm develops novel therapeutic vaccines for cancer and infectious diseases. Its product portfolio builds on its proprietary SLP-technology (Synthetic Long Peptide) for the development of therapeutic vaccines. The firm holds the exclusive rights to LUMC's patent families for amongst others, the development of therapeutic vaccines. The company was founded by Cornelis J. M. Melief in 2004 and is headquartered in Leiden, the Netherlands. | Health Technology |
ORCA Therapeutics BV
ORCA Therapeutics BV Pharmaceuticals: GenericHealth Technology ORCA Therapeutics BV designs and develops virotherapy drugs. The firm is a biopharmaceutical company focusing on the development of new anti-cancer treatments using Oncolytic Replication Competent Agents. It has a platform of technologies which are predominantly based on engineered oncolytic adenoviruses. The company was founded in 2005 and is headquartered in Nijmegen, the Netherlands. | Health Technology |
| The European CanCer Organisation | |
InteRNA Technologies BV
 InteRNA Technologies BV BiotechnologyHealth Technology InteRNA Technologies BV develops RNA technologies and applications. It provides drug discovery and development services for the treatment of cancer based on the proprietary microRNA (miRNA) functions. The company develops miRNA-based therapeutics that control genes connected in signal transduction pathways and biological processes as a part of cancer initiation, progression and metastasis. InteRNA Technologies was founded by Edwin Cuppen and Eugene Berezikov in December 2006 and is headquartered in Nijmegen, the Netherlands. | Health Technology |
| Netherlands Society of Gene Therapy | |
SomantiX BV
SomantiX BV Miscellaneous Commercial ServicesCommercial Services SomantiX BV develops imaging and therapy of cancer through targeting of tumor blood vessels. The firm offers Somantix’ screening platform which is in combination with the binder generation technologies that allows validation of new therapeutic targets and development of new cancer medicines. The company was founded in 2008 and is headquartered in Utrecht, Netherlands. | Commercial Services |
Cristal Delivery BV
Cristal Delivery BV Pharmaceuticals: MajorHealth Technology Cristal Delivery BV develops and manufactures nanomedicines for therapeutic drug optimization. It offers pipeline, oncology, and inflammation programs. The company was founded by Joost J. M. Holthuis and Cristianne Rijcken in April 2011 and is headquartered in Maastricht, the Netherlands. | Health Technology |
| Rijksinstituut Voor Volksgezondheid En Milieu | |
Mimetas BV
 Mimetas BV BiotechnologyHealth Technology Mimetas BV develops organ-on-a-chip technology for testing of new medicines in high-throughput on miniaturized organ and disease models. It develops microfluidics-based culture plates that enable culturing and screening of a range of 3D organ and tissue models. The firm offers OrganoPlates microfluidics-based culture plates that serve as early stage screening models predicting toxic side effects and drug efficacy. The company was founded by Paul Vulto and Jos Joore in 2013 and is headquartered in Leiden, the Netherlands. | Health Technology |
Inthera Bioscience AG
Inthera Bioscience AG BiotechnologyHealth Technology Inthera Bioscience AG engages in the research in as well as development, production, and distribution of pharmaceutical, biological, and other products used in the fields of human and veterinary medicine. It also provides related consultancy services. The company was founded by Ulrich Kessler and Paramjit Singh Arora on September 20, 2013 and is headquartered in Zurich, Switzerland. | Health Technology |
Modra Pharmaceuticals BV
 Modra Pharmaceuticals BV Pharmaceuticals: MajorHealth Technology Modra Pharmaceuticals BV designs and develops oral formulations of commonly used anti-cancer drugs. It is a clinical-stage company which develops series of oral formulations of existing IV anticancer drugs which reduce the side effects common to IV formulations, thereby improving patient convenience. The company was founded in June 2010 and is headquartered in Amsterdam, the Netherlands. | Health Technology |
Macrophage Pharma Ltd.
Macrophage Pharma Ltd. BiotechnologyHealth Technology Macrophage Pharma Ltd. engages in research and experimental development on biotechnology. The company is headquartered in Berkhamsted, the United Kingdom. | Health Technology |
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