On September 29, 2022, Solid Biosciences Inc. entered into an Agreement and Plan of Merger (the Merger Agreement) by and among the company, Greenland Merger Sub LLC, AavantiBio Inc. and, solely in his capacity as equityholder representative, Doug Swirsky. The Merger Agreement provides for the acquisition of AavantiBio by the company through the merger of Transitory Subsidiary into AavantiBio, with AavantiBio surviving as a wholly owned subsidiary of the Company (the Merger). It is expected that, subject to and effective upon the closing of the Merger, Alexander (Bo) Cumbo, the current Chief Executive Officer of AavantiBio, will be appointed as the chief executive officer of the company On September 29, 2022, Ilan Ganot notified the company of his intention to resign as the company's chief executive Officer, subject to, and contingent and effective upon, the closing of the Merger (such date, the Effective Date).