Axovant Sciences Ltd. announced updates the recent advancement within its clinical programs. Pipeline Program Updates: MINDSET trial recruitment: Axovant announced completion of recruitment in the Phase 3 MINDSET study of intepirdine in patients with mild-to-moderate Alzheimer's disease. The MINDSET trial is being conducted pursuant to a Special Protocol Assessment (SPA) agreement with the U.S. Food and Drug Administration (FDA). Intepirdine Thorough QT (TQT) study: The results of the TQT study exclude significant QT interval prolongation following a supratherapeutic dose of intepirdine. Intepirdine and itraconazole drug-drug interaction study: No clinically relevant drug-drug interactions were observed between intepirdine and itraconazole, a potent inhibitor of metabolic enzymes, in a group of healthy subjects. RVT-103 proof of concept study:Axovant recently completed the first portion of a proof of concept study. In the first portion of the study, subjects were randomized to treatment with a single dose of donepezil and either placebo or a peripheral muscarinic receptor antagonist. The company remains blinded to these results. The second portion of this study has begun and will explore multiday dosing of donepezil and either placebo or a peripheral muscarinic receptor antagonist. The primary endpoint of this study is safety. The company is developing intepirdine, nelotanserin, RVT-103, and RVT-104 as potential treatments for patients with Alzheimer's disease and Lewy body dementia. The company expects the following top-line results from its ongoing clinical studies in 2017: MINDSET: Results from the MINDSET study in the third quarter of 2017. HEADWAY-DLB: Results from the Phase 2b study of intepirdine in patients with dementia with Lewy bodies, the HEADWAY-DLB study, in the fourth quarter of 2017. Nelotanserin Phase 2 Visual Hallucinations Study: Preliminary results from the first cohort of 10 patients with Lewy Body dementia in February 2017. The company expects to present additional data from all 20 patients in the study in the first half of 2017. Nelotanserin Phase 2 REM Behavior Disorder Study: Results from the Phase 2 study evaluating nelotanserin for treatment of REM Behavior Disorder in patients with dementia with Lewy bodies in the second half of 2017. Gait and Balance in Patients with Dementia Study: Results from the Phase 2 study of the effects of intepirdine on gait and balance in patients with Alzheimer's disease, dementia with Lewy bodies, and Parkinson's disease dementia in 2017. RVT-103 Proof of Concept Study: Results from the RVT-103 program in the first half of 2017.