Item 1.01 Entry into a Material Definitive Agreement.

Agreement and Plan of Merger

On February 24, 2021, Pandion Therapeutics, Inc., a Delaware corporation ("Pandion"), entered into an Agreement and Plan of Merger (the "Merger Agreement") with Merck Sharp & Dohme Corp., a New Jersey corporation ("Merck"), and Panama Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Merck ("Merger Sub").

Pursuant to the Merger Agreement, upon the terms and subject to the conditions thereof, Merger Sub will commence a tender offer (the "Offer") to acquire all of the outstanding shares of Pandion common stock (the "Shares") at an offer price of $60.00 per Share, net to the seller in cash, without interest (the "Offer Price").

The obligation of Merger Sub to purchase Shares tendered in the Offer is subject to the satisfaction or waiver of the conditions set forth in Annex I to the Merger Agreement, including (i) that there shall have been validly tendered and not validly withdrawn that number of Shares that, when added to any Shares then owned by Merck and its controlled affiliates, represent at least one Share more than half of the sum of (A) all Shares then outstanding as of the expiration of the Offer, and (B) all Shares that Pandion may be required to issue upon the vesting (including vesting solely as a result of the consummation of the Offer), conversion, settlement or exercise of all then outstanding warrants, options, benefit plans, obligations or securities convertible or exchangeable into Shares, or other rights to acquire or be issued Shares, regardless of the conversion or exercise price or other terms and conditions thereof (the "Minimum Condition"); (ii) the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended (the "HSR Act") and receipt of clearance, approval or consent under any other applicable antitrust law; and (iii) those other conditions set forth in Annex I to the Merger Agreement.

Following the consummation of the Offer and upon the terms and subject to the conditions of the Merger Agreement, Merger Sub will merge with and into Pandion, with Pandion surviving as a wholly owned subsidiary of Merck (the "Merger"). In the Merger, each Share issued and outstanding immediately prior to the effective time (the "Effective Time") of the Merger (other than certain excluded Shares as described in the Merger Agreement) will automatically be converted into the right to receive the Offer Price.

In addition, immediately prior to the Effective Time, each unexpired and unexercised option to purchase Shares under any Pandion stock plan (each, a "Company Stock Option"), shall, to the extent unvested, become fully vested and exercisable immediately prior to, and contingent upon, the Effective Time. At the Effective Time, each Company Stock Option shall be cancelled and converted into the right to receive, a payment in cash equal to the product of (i) the total number of Shares subject to such Company Stock Option immediately prior to such cancellation and (ii) the excess, if any, of the Offer Price over the exercise price per Share subject to such Company Stock Option immediately prior to such cancellation. No holder of a Company Stock Option that, as of immediately prior to such cancellation, has an exercise price per Share that is equal to or greater than the Offer Price shall be entitled to any payment with respect to such cancelled Company Stock Option.

The Merger Agreement includes representations, warranties and covenants of the parties customary for a transaction of this nature. Among other things, until the earlier of the termination of the Merger Agreement or the Effective Time, Pandion has agreed to operate its business in the ordinary and usual course consistent with past practice and has agreed to certain other operating covenants, as set forth fully in the Merger Agreement. The Merger Agreement also prohibits Pandion's solicitation of proposals relating to alternative transactions and restricts Pandion's ability to furnish information to, or participate in any discussions or negotiations with, any third party with respect to any such transaction, subject to certain limited exceptions.

Either Pandion or Merck may terminate the Merger Agreement in certain circumstances, including if (i) the Offer is not completed by June 24, 2021, subject to automatic extension in the event that antitrust approval has not been obtained (the "Outside Date"), (ii) a governmental authority of a jurisdiction in which Merck or any of its affiliates operate their respective businesses or own assets has issued a final non-appealable judgment preventing the consummation of the Offer or the Merger or any applicable law by such a governmental authority makes

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consummation of the Offer or the Merger illegal, (iii) the Offer has expired without the acceptance of the Shares for payment, in a circumstance in which all of the conditions to the Offer have been satisfied or waived (other than the Minimum Condition), following extension of the Offer pursuant to the Merger Agreement or (iv) the other party breaches its representations, warranties or covenants in the Merger Agreement in a way that would cause any condition of the Offer not to be satisfied, subject to the right of the breaching party to cure the breach. In addition, Pandion may terminate the Merger Agreement, subject to compliance with specified process and notice requirements, in order to enter into an agreement with a third party who has made a "Superior Proposal" (as defined in the Merger Agreement), and Merck may terminate the Merger Agreement if Pandion's board of directors has changed its recommendation in favor of the Offer and the Merger, failed to include its recommendation in the Schedule 14D-9, failed to reaffirm its recommendation when requested by Merck or has taken certain other actions described in the Merger Agreement (each a "Company Adverse Recommendation Change"); or if Pandion has violated or breached in any material respect the non-solicitation provision of the Merger Agreement.

In the event of a termination of the Merger Agreement under certain specified circumstances, including (i) termination by Pandion to enter into an agreement providing for a Superior Proposal, (ii) termination by Merck following a Company Adverse Recommendation Change, (iii) termination by Merck because Pandion has violated or breached in any material respect the non-solicitation provision, or (iv) termination because (A) after the date of the Merger Agreement an "Acquisition Proposal" (as defined in the Merger Agreement) has either been made to Pandion or been publicly made directly to Pandion's stockholders; (B)(1) the Outside Date has occurred, (2) the Offer has expired without the acceptance of the Shares for payment, or (3) Pandion has breached and not cured any representation, warranty or covenant such that a condition to the Offer is not capable of being satisfied; and (C) within twelve months following (B)(1), (2) or (3), Pandion or any of its subsidiaries signs a definitive agreement for an Acquisition Proposal or consummates an Acquisition Proposal, Pandion may be required to pay Merck a termination fee equal to $65,000,000. . . .

Item 5.02 Departure of Directors or Certain Officers; Election of Directors;

Appointment of Certain Officers; Compensatory Arrangements of Certain

Officers.

Concurrent with the entry into the Merger Agreement, Jo Viney, Ph.D., President and Chief Scientific Officer of Pandion, entered into a retention agreement with Pandion (the "Retention Agreement"), which provides Dr. Viney with (i) base salary of $450,000 per year, (ii) annual target bonus of 40% of the base salary and (iii) a retention bonus equal to 100% of the base salary, generally subject to Dr. Viney's continued employment with Pandion for a period of 6 months following the consummation of the Merger. The Retention Agreement becomes effective as of the Closing (as defined in the Merger Agreement) and is conditioned on completion of the Merger.

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Item 8.01 Other Events.

On February 25, 2021, Pandion and Merck issued a joint press release announcing the execution of the Merger Agreement. A copy of the press release is attached to this Current Report as Exhibit 99.2 and is incorporated herein by reference.

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Item 9.01 Financial Statements and Exhibits.




(d) Exhibits



Exhibit
Number       Description

 2.1           Agreement and Plan of Merger, dated February 24, 2021, among Pandion
             Therapeutics, Inc., Merck Sharp & Dohme Corp. and Panama Merger Sub,
             Inc.*

99.1           Form of Tender and Support Agreement, among Merck Sharp & Dohme
             Corp., Panama Merger Sub, Inc. and certain stockholders of Pandion
             Therapeutics, Inc.

99.2           Joint Press Release, dated February 25, 2021.



* Schedules to the Agreement and Plan of Merger have been omitted pursuant to

Item 601(b)(2) of Regulation S-K. The registrant will furnish copies of any

such schedules to the U.S. Securities and Exchange Commission upon request.

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