On December 23, 2015, the Board of Directors of POZEN Inc. appointed Scott Charles as Chief Financial Officer of the Company and Eric L. Trachtenberg as General Counsel, Chief Compliance Officer and Corporate Secretary of the Company, both effective January 1, 2016. On December 23, 2015, William L. Hodges, Gilda M. Thomas and Dennis L. McNamara have resigned as executive officers of Company, effective January 1, 2016. Mr. Hodges, formerly Senior Vice President and Chief Financial Officer, will remain with the Company as Senior Vice President, Finance through the end of the first quarter of 2016.

Ms. Thomas, formerly Senior Vice President, General Counsel and Secretary, and Mr. McNamara, formerly Senior Vice President, Chief Business Operations Officer, will be leaving the Company on a full time basis as of January 8, 2015, but will continue as a part-time employees until completion of the pending merger of the Company with Tribute Pharmaceuticals Canada Inc. (“Tribute”). Prior to joining the Company, Mr. Charles served as the Vice President of Finance and Treasurer at Ikaria Inc. from April 2008 to July 2015.