On January 14, 2021, Nkarta, Inc. entered into a Third Amendment to Lease by and between the Company and HCP Life Science REIT, Inc., which amends that certain Lease, dated as of May 29, 2018, by and between the Company and the Landlord, for office and laboratory space in South San Francisco, California. The Amendment expands the 2018 Leased Premises to include approximately an additional 5,601 square feet of space in Suite 201 and Suite 203 on the second floor of the Company’s headquarters at 6000 Shoreline Court in South San Francisco, California for a total of 34,070 square feet, at the monthly base rent for the Third Expansion Premises. The term for the Third Extension Premises commences on April 1, 2021 and expires on March 31, 2024. The other terms of the 2018 Lease remain unchanged.