Item 1.01 Entry into a Material Definitive Agreement.

On January 14, 2021, Nkarta, Inc. (the "Company") entered into a Third Amendment to Lease (the "Amendment") by and between the Company and HCP Life Science REIT, Inc. (the "Landlord"), which amends that certain Lease, dated as of May 29, 2018 (as amended from time to time, the "2018 Lease"), by and between the Company and the Landlord, for office and laboratory space in South San Francisco, California (the "2018 Leased Premises"). The Amendment expands the 2018 Leased Premises to include approximately an additional 5,601 square feet of space in Suite 201 and Suite 203 (the "Third Expansion Premises") on the second floor of the Company's headquarters at 6000 Shoreline Court in South San Francisco, California (the "Building") for a total of 34,070 square feet, at the monthly base rent for the Third Expansion Premises indicated in the table below:



                Period                         Monthly Base Rent
                April 1, 2021 - March 31, 2022    $18,203.25
                April 1, 2022 - March 31, 2023    $18,840.36
                April 1, 2023 - March 31, 2024    $19,499.78

The term for the Third Extension Premises commences on April 1, 2021 and expires on March 31, 2024. The other terms of the 2018 Lease remain unchanged.

The foregoing summary of the Amendment does not purport to be complete and is qualified in its entirety by reference to the Amendment, which the Company expects to file as an exhibit to its Annual Report on Form 10-K for the year ended December 31, 2020.

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