"We are pleased that our study with MIV-711 in osteoarthritis has been published in a highly reputable scientific journal and that an editorial in the same issue suggests that our study may point to a way forward for disease modifying medicines for osteoarthritis", said Dr
For further information, please contact:
About osteoarthritis
Up to 40 percent of the population over 65 suffer from osteoarthritis (OA), characterized by pain and varying degrees of inflammation in one or more joints, mainly knees, hips and hands. Osteoarthritis in weight-bearing joints, like knees and hips, induces an increasing level of pain and decreased mobility for the patient, and may eventually result in joint replacement surgery. Drugs capable of slowing, stopping or even reversing the progression of the disease are referred to as Disease Modifying Osteoarthritis Drugs (DMOAD). There is currently no such therapy approved for osteoarthritis and current treatments affect only day to day symptoms without affecting degenerative changes in the diseased joint.
About MIV-711
MIV-711 is a potent and selective inhibitor of cathepsin K, the principal protease involved in breaking down collagen in bone and cartilage. It is being developed to slow, stop or reverse the progressive degeneration of joints affected by osteoarthritis, and is therefore a potential DMOAD.
About
https://news.cision.com/medivir/r/medivir-s-phase-ii-study-of-miv-711-in-patients-with-osteoarthritis-published-in-annals-of-internal-,c3011596
https://mb.cision.com/Main/652/3011596/1176545.pdf
(c) 2020 Cision. All rights reserved., source