Medivir AB announced the successful completion of the pre-clinical safety studies for MIV-818 to enable the start of phase I clinical trials in 2018. MIV-818 is Medivir's proprietary liver-targeted nucleotide prodrug for the treatment of hepatocellular carcinoma (HCC) and other forms of liver cancer. It is the first development project to emerge from Medivir's in-house drug discovery efforts in oncology. With the successful completion of the pre-clinical safety studies on MIV-818, Medivir intends to make the necessary regulatory submissions during the first half of 2018, and to start the first clinical trials of MIV-818 during the second half of 2018.