Lumos Pharma Appoints David B. Karpf as Chief Medical Officer
August 03, 2021 at 05:30 pm IST
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Lumos Pharma, Inc. has announced that experienced endocrinologist and pharma executive, David B. Karpf joined the Company August 3, 2021 as its new Chief Medical Officer. David B. Karpf, MD is an academically trained endocrinologist with over 35 years of expertise in all aspects of clinical endocrinology. He is also an accomplished biopharmaceutical executive with 30 years of experience in the development of biopharmaceuticals and small molecular weight drugs in the areas of endocrinology, rare diseases, and autoimmune disease, among others. Dr. Karpf’s extensive experience spans all facets of biopharmaceutical clinical development from preclinical to Phase 4 – including successful interactions with US and international regulatory agencies, and marketing/launch activities – and he has contributed substantially to 6 NDAs.
Lumos Pharma, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in advancing its clinical program and focused on identifying, acquiring, developing, and commercializing products and new therapies for people with rare diseases. Its pipeline is focused on the development of an orally administered small molecule, LUM-201, which is a growth hormone (GH) secretagogue, also called ibutamoren, for rare endocrine disorders that require injectable recombinant human growth hormone (rhGH). LUM-201 is a tablet formulation that is intended to be administered once daily. LUM-201 stimulates GH via the GH secretagogue receptor (GHSR1a), also known as the ghrelin receptor, and also suppresses the release of somatostatin, thus providing a differentiated mechanism of action to treat some rare endocrine disorders (involving a deficiency of GH) by increasing the amplitude of endogenous, pulsatile GH secretion. Lumos Pharma Sub, Inc. (Private Lumos) is its subsidiary.