Acucela Inc. announced that Brian O'Callaghan, the company's President and Chief Operating Officer, will assume the role of Chief Executive Officer, along with continuing to serve as Interim Chief Financial Officer. Ryo Kubota, M.D., Ph.D., the company's Founder, will retain his position as Chairman of the company's Board of Directors. Mr. O'Callaghan will assume the role of CEO effective January 1, 2015.