Kronos Bio, Inc. announced that on January 21, 2023, Marianne De Backer, Ph.D., notified the company of her decision to resign from board of directors as a result of her recent appointment as Chief Executive Officer of Vir Biotechnology, Inc., and in consideration of her additional time commitments associated with such position, as well as the 'overboarding' policies of shareholder advisory firms. The effective date of the resignation has not yet been established, but Dr. De Backer informed the company it would likely be late in the first quarter or in the second quarter of 2023. The company will file an amendment to this current report on Form 8-K to report the effective date of Dr. De Backer's resignation within four business days of the effective date being determined.