Syncona Limited (LSE:SYNC) that its investment manager has submitted a proposal to buy the shares of Freeline Therapeutics Holdings plc (NasdaqCM:FRLN) that it doesn't already own, and plans to start talks with the company over a potential deal. The U.K. healthcare company said Wednesday that it is offering to pay $5.00 for each American Depositary Share of Freeline, a 20% premium over the volume weighted average price of $4.16 between Oct. 4 and Oct.

16. Syncona, which currently owns approximately 57.9% of Freeline, said there isn't a guarantee that any deal will be agreed. Syncona shares at 10:30 GMT were up 0.20 pence, or 0.2%, at 126.20 pence.