Inactive Instrument

Forty Seven, Inc.

Equities

US34983P1049

Biotechnology & Medical Research

Forty Seven Inc. to Collaborate with Merck Kgaa, Darmstadt, Germany, on Novel Immuno-Oncology Combination for Ovarian Cancer

January 11, 2018 at 06:00 pm IST

Forty Seven Inc. announced an agreement with Merck KGaA, Darmstadt, Germany to conduct a Phase 1b clinical trial combining Hu5F9-G4 with avelumab in patients with ovarian cancer. PD-L1 and CD47 are immunosuppressant molecules overexpressed on cancer cells that send inhibitory signals to T cells and macrophages, respectively. Binding of avelumab to PD-L1 takes the brakes off T cells and, in a similar way, binding of Hu5F9-G4 to CD47 takes the brakes off macrophages.

Latest news about Forty Seven, Inc.

Forty Seven, Inc.(NasdaqGS:FTSV) dropped from S&P TMI Index	07/20/07	CI
Forty Seven, Inc.(NasdaqGS:FTSV) dropped from S&P Global BMI Index	07/20/07	CI
Gilead Sciences, Inc. completed the acquisition of Forty Seven, Inc..	06/20/06	CI
Forty Seven, Inc. Reports Earnings Results for the Fourth Quarter Ended December 31, 2019	21/20/21	CI
Forty Seven and Rocket Pharmaceuticals Announce Research Collaboration for Fanconi Anemia	11/20/11	CI
Certain Common Stock of Forty Seven, Inc. are subject to a Lock-Up Agreement Ending on 11-MAR-2020.	11/20/11	CI
Certain Stock Options of Forty Seven, Inc. are subject to a Lock-Up Agreement Ending on 11-MAR-2020.	11/20/11	CI
Forty Seven : Thermo Fisher agrees to buy genetic tester Qiagen in $11.5 billion deal	03/20/03	RE
Forty Seven : Gilead buys Forty Seven for $4.9 billion to bolster cancer drug pipeline	02/20/02	RE
Gilead Sciences, Inc. entered into a definitive agreement to acquire Forty Seven, Inc. for $4.6 billion.	02/20/02	CI
Gilead Sciences Reportedly Approaches Forty Seven with a Takeover Offer	28/20/28	CI
Transcript : Forty Seven, Inc. - Special Call	10/19/10
Forty Seven, Inc. Announces Foundational Preclinical Data Supporting the Development of FSI-174 in Combination with Magrolimab as a Novel All Antibody Conditioning Regimen for Hematopoietic Stem Cell Transplantation	09/19/09	CI
Forty Seven, Inc. Announces Updated Data from Ongoing Clinical Trial of Magrolimab	09/19/09	CI
Transcript : Forty Seven, Inc., Q3 2019 Earnings Call, Nov 12, 2019	12/19/12
Forty Seven, Inc. Reports Earnings Results for the Third Quarter Ended September 30, 2019	12/19/12	CI
Bluebird bio and Forty Seven Announce a Research Collaboration to Study an All Antibody Conditioning Regimen for Use in Combination with Autologous Lentiviral Vector Hematopoietic Stem Cell Gene Therapy	12/19/12	CI
Forty Seven, Inc. to Present New Clinical and Preclinical Data on Magrolimab and FSI-174 at 61st ASH Annual Meeting	06/19/06	CI
Certain Common Stock of Forty Seven, Inc. are subject to a Lock-Up Agreement Ending on 17-OCT-2019.	17/19/17	CI
Certain Stock Options of Forty Seven, Inc. are subject to a Lock-Up Agreement Ending on 17-OCT-2019.	17/19/17	CI
U.S., Canada and Mexico business leaders say tariffs erode business expansion	24/19/24	RE
Forty Seven, Inc.(NasdaqGS:FTSV) added to S&P Global BMI Index	23/19/23	CI
Transcript : Forty Seven, Inc. Presents at Morgan Stanley 17th Annual Global Healthcare Conference, Sep-10-2019 02:55 PM	11/19/11
Forty Seven, Inc. Receives Fast Track Designation for Magrolimab for the Treatment of Myelodysplastic Syndrome and Acute Myeloid Leukemia	03/19/03	CI
Transcript : Forty Seven, Inc., Q2 2019 Earnings Call, Aug 13, 2019	14/19/14

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Forty Seven, Inc. is clinical-stage immuno-oncology company. The Company is focused on developing novel checkpoint therapies to activate macrophages in the fight against cancer. The Company's lead product candidate, 5F9, is a humanized IgG4 subclass monoclonal antibody against CD47 that is designed to interfere with recognition of CD47 by the SIRPa receptor on macrophages. The Company's another product FSI-189, is an antibody that binds to SIRPa and initiate Phase I solid tumor trials for FSI-189. The Company is investigating 5F9 in multiple Phase I and Phase II trials in various cancers including acute myeloid leukemia (AML), non-Hodgkin's lymphoma (NHL) and colorectal carcinoma (CRC), and ovarian cancer, as both a monotherapy and in combination with other therapies, such as rituximab and cetuximab. In addition to the 5F9, which is an antibody that binds to CD47 blocking its binding to SIRPa.

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