Certain Common Stock of Flexion Therapeutics, Inc. are subject to a Lock-Up Agreement Ending on 9-JAN-2018. These Common Stock will be under lockup for 90 days starting from 11-OCT-2017 to 9-JAN-2018. Details: The certain of our officers and directors, and certain of their affiliated entities have agreed that they will not directly or indirectly, offer, sell, pledge, contract to sell, grant any option to purchase or otherwise dispose of any shares of company’s common stock, shares of common stock which may be issued upon exercise of a stock option or warrant and any other security convertible into or exchangeable for company’s common stock, or enter into any hedging transaction relating to company’s common stock, for a period of 90 days from the date of this prospectus without the prior written approval of Wells Fargo Securities, LLC and BMO Capital Markets Corp.