On October 15, 2022, Enzo Biochem, Inc. (the Company) received written notice from David Bench that he was tendering his resignation as Senior Vice President, Treasurer and Corporate Secretary of the Company, effective November 14, 2022. His decision to resign was not due to any disagreement with the Company on any matter relating to the Company's operations, policies or practices (financial or otherwise). The Company has accepted Mr. Bench's resignation, effective as of November 14, 2022.