On May 07, 2021, the Board of Directors of Aptinyx Inc. unanimously appointed Dr. Joan Miller to the Board. Upon her appointment to the Board, Dr. Miller became a member of the class of directors with terms expiring at the 2023 Annual Meeting of Stockholders of the Company. At the time of Dr. Miller’s appointment to the Board, the committees of the Board to which Dr. Miller will be or is expected to be appointed, if any, had not been determined. Dr. Miller, currently serves as the David Glendenning Cogan Professor of Ophthalmology and Chair of the Department of Ophthalmology at Harvard Medical School, as well as Chief of Ophthalmology at both Massachusetts Eye and Ear and Massachusetts General Hospital. Dr. Miller is also a member of the National Academy of Medicine, a Gold Fellow of the Association for Research in Vision and Ophthalmology (ARVO), and has served on numerous Scientific Advisory Boards across the biopharmaceutical industry. She was the co-recipient of the 2014 António Champalimaud Vision Award.