Item 2.02Results of Operations and Financial Condition.

On May 15, 2023, Aprea Therapeutics, Inc. (the "Company") issued a press release announcing its financial results for the three months ended March 31, 2023, and provided an update on the Company's operations for the same period. The Company is furnishing a copy of the press release, which is attached hereto as Exhibit 99.1.

In accordance with General Instruction B.2 of Form 8-K, the information included in this Item 2.02, including Exhibit 99.1 hereto, shall not be deemed "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference into any filing made by the Company under the Exchange Act or Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such a filing.

Item 8.01Other Events.

On May 15, 2023, the Company updated its corporate presentation slide deck. A copy of the corporate presentation slide deck is filed as Exhibit 99.2 hereto and incorporated herein by reference.

Item 9.01Financial Statements and Exhibits.

(d) Exhibits.



Exhibit
 Number                                 Description
  99.1        Press release issued by Aprea Therapeutics, Inc. dated May 15,
            2023.
  99.2        Corporate Presentation (May 2023).
            Cover Page Interactive Data File (embedded within the inline XBRL
  104       document).

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