New technique renders brain 'transparent,' allows scientists to reconstruct neural circuitry
January 2, 2018
Until recently, the composition of brain tissue limited researchers' insights into the brain's neural circuitry and function.
NSF-funded scientists developed a technique called CLARITY to chemically dissolve opaque elements and replace them with a hydrogel, essentially rendering the brain transparent. When used with fluorescent markers, CLARITY lets researchers precisely reconstruct the brain's neural circuitry in 3-D and analyze how changes to the brain may underlie certain disorders such as autism or depression.
The technique has been hailed as a breakthrough in neuroscience.
NSF Directorate(s):
Directorate for Biological Sciences
Locations
California
Related Awards
#0724593 In vivo Technology for Fast Optical Control of Neural Circuits
Related Websites
CLARITY opens window to brain circuitry, new era for neuroscience: https://nsf.gov/news/mmg/mmg_disp.jsp?med_id=78002&from=
NSF - National Science Foundation published this content on 02 January 2018 and is solely responsible for the information contained herein.
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