Medtronic plc is one of the world leaders in designing, manufacturing and marketing of medical equipment. Net sales break down by sector of activity as follows: - general and minimally invasive surgery (25%): surgical equipment, intra-operative monitoring systems, ventilation systems, etc.; - cardiac rhythm management (19%): implantable cardiac pacemakers, implantable defibrillators and automatic external defibrillators, cardiac ablation probes, etc.; - vascular diseases and cardiac surgery (18.1%): coronary stents, endoprostheses for aortal pathologies, distal protection systems, catheters, heart valve prostheses, auto-transfusion equipment, cardiac ablation devices, etc.; - cranial and spinal technologies (14.8%): spinal prostheses, disc prostheses, cerebral stimulation systems, bone graft technologies and mini-invasive spinal surgery, etc. The group also develops medical imagery-guided surgical navigation systems activity; - neurovascular, ear, nose and throat (ENT) and pelvic diseases (8.7%); - diabetes management (8.2%): internal and external glycemia monitoring systems and insulin pumps; - neurological disorders (5.7%): neurostimulation and pumped medication administration products, diagnostic tools, etc. ; - other (0.5%). Net sales are distributed geographically as follows: Ireland (0.3%), the United States (51.2%) and other (48.5%).