Valuation: ISIS Pharmaceuticals, Inc.

Market Cap 1.03TCr 883.57Cr 826.59Cr 755.71Cr 1.43TCr 99TCr 1.44TCr 9.78TCr 3.8TCr 50TCr 3.87TCr 3.79TCr 1,64000Cr P/E 2026 *
-17x
P/E 2027 * -32.8x
Enterprise Value 1.02TCr 874.75Cr 818.33Cr 748.16Cr 1.41TCr 98TCr 1.43TCr 9.68TCr 3.77TCr 49TCr 3.83TCr 3.75TCr 1,62400Cr EV / Sales 2026 *
11.2x
EV / Sales 2027 * 7.39x
Free-Float
99.05%
Yield 2026 *
-
Yield 2027 * -
Manager TitleAgeSince
Investor Relations Contact 60 01/07/2012
Chief Executive Officer 64 01/01/2020
Director of Finance/CFO 64 01/05/2000
Director TitleAgeSince
Director/Board Member 64 13/12/2005
Director/Board Member 73 01/05/2002
Director/Board Member 64 25/03/2019
Change 5-day change 1-year change 3-year change Capi.($)
+1.33%+2.73% - - 1.03TCr
+0.85%+4.98%+3.70%+25.50% 5.12TCr
+1.01%-0.20%+471.68%+564.93% 4.53TCr
+0.16%+7.88%+36.14%+20.76% 4.28TCr
-0.66%+2.61%+18.59%+87.04% 4.23TCr
+0.88%-3.48%+17.20%+53.83% 3.22TCr
-0.12%+3.84%+33.73%+145.25% 1.73TCr
-0.53%+1.84% - - 1.65TCr
+0.27%+5.46%+10.07%+31.51% 1.48TCr
+1.15%+4.17%+84.49%+50.33% 1.43TCr
Average +0.43%+3.23%+84.45%+122.39% 3.08TCr
Weighted average by Cap. +0.42%+3.07%+101.46%+141.89%

Financials

2026 *2027 *
Net sales 91Cr 78Cr 73Cr 67Cr 126.34Cr 8.75TCr 127.68Cr 866.54Cr 336.94Cr 4.39TCr 342.95Cr 335.53Cr 15TCr 140.21Cr 120.16Cr 112.41Cr 102.77Cr 193.94Cr 13TCr 196Cr 1.33TCr 517.23Cr 6.74TCr 526.45Cr 515.05Cr 22TCr
Net income -60Cr -52Cr -48Cr -44Cr -83Cr -5.77TCr -84Cr -571.52Cr -222.23Cr -2.9TCr -226.19Cr -221.3Cr -9.58TCr -33Cr -28Cr -26Cr -24Cr -45Cr -3.12TCr -46Cr -309.14Cr -120.21Cr -1.57TCr -122.35Cr -119.7Cr -5.18TCr
Net Debt -10Cr -8.82Cr -8.25Cr -7.55Cr -14Cr -985.91Cr -14Cr -98Cr -38Cr -495.07Cr -39Cr -38Cr -1.64TCr 5.75Cr 4.92Cr 4.61Cr 4.21Cr 7.95Cr 550.14Cr 8.03Cr 55Cr 21Cr 276.25Cr 22Cr 21Cr 914Cr
Logo ISIS Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
Employees
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Global
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Quality
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ESG MSCI
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