Valuation: ISIS Pharmaceuticals, Inc.

Market Cap 898.86Cr 785.52Cr 724.85Cr 668.13Cr 1.26TCr 87TCr 1.29TCr 8.66TCr 3.41TCr 42TCr 3.38TCr 3.3TCr 1,45900Cr P/E 2026 *
-15x
P/E 2027 * -29.6x
Enterprise Value 873.61Cr 763.45Cr 704.49Cr 649.37Cr 1.22TCr 84TCr 1.25TCr 8.42TCr 3.31TCr 41TCr 3.28TCr 3.21TCr 1,41800Cr EV / Sales 2026 *
9.82x
EV / Sales 2027 * 6.41x
Free-Float
99.09%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: ISIS Pharmaceuticals, Inc.

Manager TitleAgeSince
Investor Relations Contact 60 01/07/2012
Chief Executive Officer 64 01/01/2020
Director of Finance/CFO 64 01/05/2000
Director TitleAgeSince
Director/Board Member 64 13/12/2005
Director/Board Member 73 01/05/2002
Director/Board Member 64 25/03/2019
Change 5-day change 1-year change 3-year change Capi.($)
+1.33%+2.73% - - 898.86Cr
+3.90%-0.39%+376.72%+599.59% 3.96TCr
-1.70%+4.46%+7.46%+57.67% 3.47TCr
-2.01%-0.76%+26.35%-6.83% 3.44TCr
+0.06%+0.34%+2.32%+29.30% 2.71TCr
+0.46%-3.49% - - 1.62TCr
-0.04%-0.09%+68.48%+117.39% 1.54TCr
+1.12%+1.91%+15.90%+19.65% 1.41TCr
0.00%+1.36%+15.74%-30.62% 1.3TCr
-0.08%-3.01%+1,271.69%+649.69% 1.18TCr
Average +0.30%+0.04%+223.08%+179.48% 2.29TCr
Weighted average by Cap. +0.29%+0.36%+171.43%+187.42%

Financials

2026 *2027 *
Net sales 89Cr 78Cr 72Cr 66Cr 124.57Cr 8.56TCr 127.34Cr 857.05Cr 337.1Cr 4.19TCr 333.93Cr 326.6Cr 14TCr 138.86Cr 121.35Cr 111.97Cr 103.21Cr 194.54Cr 13TCr 198.86Cr 1.34TCr 526.42Cr 6.55TCr 521.47Cr 510.03Cr 23TCr
Net income -60Cr -52Cr -48Cr -44Cr -84Cr -5.76TCr -86Cr -576.61Cr -226.79Cr -2.82TCr -224.66Cr -219.73Cr -9.71TCr -31Cr -27Cr -25Cr -23Cr -43Cr -2.98TCr -44Cr -298.13Cr -117.26Cr -1.46TCr -116.16Cr -113.61Cr -5.02TCr
Net Debt -25Cr -22Cr -20Cr -19Cr -35Cr -2.43TCr -36Cr -243.36Cr -96Cr -1.19TCr -95Cr -93Cr -4.1TCr -8.62Cr -7.53Cr -6.95Cr -6.4Cr -12Cr -829.72Cr -12Cr -83Cr -33Cr -406.36Cr -32Cr -32Cr -1.4TCr
Logo ISIS Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
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