Valuation: ISIS Pharmaceuticals, Inc.

Market Cap 893.08Cr 778.78Cr 726.63Cr 668.15Cr 1.25TCr 85TCr 1.28TCr 8.61TCr 3.37TCr 42TCr 3.35TCr 3.28TCr 1,45900Cr P/E 2026 *
-16.8x
P/E 2027 * -30.4x
Enterprise Value 862.87Cr 752.43Cr 702.04Cr 645.54Cr 1.21TCr 83TCr 1.24TCr 8.32TCr 3.25TCr 41TCr 3.24TCr 3.17TCr 1,41000Cr EV / Sales 2026 *
8.8x
EV / Sales 2027 * 6.22x
Free-Float
99.08%
Yield 2026 *
-
Yield 2027 * -
Manager TitleAgeSince
Investor Relations Contact 60 01/07/2012
Chief Executive Officer 64 01/01/2020
Director of Finance/CFO 64 01/05/2000
Director TitleAgeSince
Director/Board Member 64 13/12/2005
Director/Board Member 73 01/05/2002
Director/Board Member 64 25/03/2019
Change 5-day change 1-year change 3-year change Capi.($)
+1.33%+2.73% - - 914.23Cr
+2.61%+1.91%+1.70%+13.91% 4.79TCr
-1.60%-1.29%+385.56%+603.70% 3.91TCr
-0.98%+2.68%+11.10%+45.34% 3.67TCr
+1.90%+22.79%+25.18%+9.47% 4.05TCr
+1.47%+4.90%+6.48%+43.52% 2.8TCr
-0.94%-1.23% - - 1.68TCr
+2.44%+10.02%+29.11%+129.56% 1.59TCr
+0.18%-1.46%+4.92%+10.14% 1.36TCr
-1.14%+6.94%-6.05%-29.33% 1.38TCr
Average +0.53%+4.66%+57.25%+103.29% 2.8TCr
Weighted average by Cap. +0.64%+5.06%+73.07%+124.52%

Financials

2026 *2027 *
Net sales 98Cr 86Cr 80Cr 73Cr 137.73Cr 9.38TCr 141.02Cr 946.15Cr 369.83Cr 4.65TCr 368.3Cr 360.31Cr 16TCr 139.67Cr 121.79Cr 113.64Cr 104.49Cr 196.09Cr 13TCr 200.78Cr 1.35TCr 526.53Cr 6.62TCr 524.35Cr 512.98Cr 23TCr
Net income -53Cr -46Cr -43Cr -40Cr -75Cr -5.08TCr -76Cr -511.85Cr -200.07Cr -2.52TCr -199.24Cr -194.92Cr -8.67TCr -28Cr -25Cr -23Cr -21Cr -40Cr -2.72TCr -41Cr -274.48Cr -107.29Cr -1.35TCr -106.84Cr -104.53Cr -4.65TCr
Net Debt -30Cr -26Cr -25Cr -23Cr -42Cr -2.89TCr -43Cr -291.4Cr -113.9Cr -1.43TCr -113.43Cr -110.97Cr -4.94TCr -24Cr -21Cr -20Cr -18Cr -34Cr -2.3TCr -34Cr -231.46Cr -90Cr -1.14TCr -90Cr -88Cr -3.92TCr
Logo ISIS Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
Employees
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Global
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ESG MSCI
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