Valuation: ISIS Pharmaceuticals, Inc.

Market Cap 1.35TCr 1.18TCr 1.09TCr 1.01TCr 1.92TCr 1,28700Cr 1.95TCr 13TCr 5.07TCr 63TCr 5.07TCr 4.97TCr 2,18000Cr P/E 2026 *
-22.7x
P/E 2027 * -65x
Enterprise Value 1.33TCr 1.16TCr 1.07TCr 995.85Cr 1.89TCr 1,26600Cr 1.92TCr 13TCr 4.99TCr 62TCr 4.99TCr 4.88TCr 2,14500Cr EV / Sales 2026 *
14.9x
EV / Sales 2027 * 8.89x
Free-Float
99.09%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: ISIS Pharmaceuticals, Inc.

Manager TitleAgeSince
Investor Relations Contact 60 01/07/2012
Chief Executive Officer 64 01/01/2020
Director of Finance/CFO 64 01/05/2000
Director TitleAgeSince
Director/Board Member 64 13/12/2005
Director/Board Member 73 01/05/2002
Director/Board Member 64 25/03/2019
Change 5-day change 1-year change 3-year change Capi.($)
+1.33%+2.73% - - 1.35TCr
+1.70%+7.41%+2.50%+8.22% 4.99TCr
+0.92%+3.93%+399.71%+605.33% 4.02TCr
+1.89%+8.32%+26.06%-6.35% 3.46TCr
+2.38%+6.35%+21.25%+64.58% 3.31TCr
+3.96%+10.67%+8.30%+40.44% 2.75TCr
+2.51%+5.27% - - 1.7TCr
+2.58%+5.79%+73.44%+133.27% 1.59TCr
+0.32%+0.58%+14.00%+19.59% 1.39TCr
+5.63%+59.76%+1,820.34%+785.83% 1.33TCr
Average +2.32%+11.97%+295.70%+206.36% 2.73TCr
Weighted average by Cap. +2.15%+9.54%+191.03%+177.96%

Financials

2026 *2027 *
Net sales 89Cr 78Cr 72Cr 67Cr 126.9Cr 8.51TCr 128.82Cr 861.68Cr 334.98Cr 4.18TCr 335.35Cr 328.15Cr 14TCr 150.51Cr 131.57Cr 120.92Cr 112.71Cr 213.77Cr 14TCr 217.02Cr 1.45TCr 564.31Cr 7.04TCr 564.94Cr 552.81Cr 24TCr
Net income -60Cr -52Cr -48Cr -45Cr -85Cr -5.7TCr -86Cr -577.17Cr -224.37Cr -2.8TCr -224.62Cr -219.8Cr -9.65TCr -20Cr -17Cr -16Cr -15Cr -28Cr -1.89TCr -29Cr -191.5Cr -74Cr -929.29Cr -75Cr -73Cr -3.2TCr
Net Debt -22Cr -19Cr -18Cr -16Cr -31Cr -2.09TCr -32Cr -212.21Cr -82Cr -1.03TCr -83Cr -81Cr -3.55TCr -14Cr -12Cr -11Cr -10Cr -20Cr -1.32TCr -20Cr -133.26Cr -52Cr -646.67Cr -52Cr -51Cr -2.23TCr
Logo ISIS Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc. develops six marketed medicines for serious diseases, including medicines for neurologic and cardiovascular diseases. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.
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